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AFE159RP4

ACTIVE

Low-power 4-channel ECG AFE with respiration, pacemaker, lead-off & lead quality detection, and FIFO

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Data sheet

AFE159RP4

ACTIVE
Data sheet Order now

Product details

Applications AEDs, Bedside patient monitoring and diagnostic ECG, ECG patch, EEG, EMG, Event, Evoked audio potential (EAP), Holter monitor and multi-lead patch, Portable telemetry, Respiration, Sleep study monitor, Telemedicine bispectral index (BIS) Number of input channels 4 Resolution (Bits) 24 Interface type SPI Operating temperature range (°C) -20 to 85 Rating Catalog
Applications AEDs, Bedside patient monitoring and diagnostic ECG, ECG patch, EEG, EMG, Event, Evoked audio potential (EAP), Holter monitor and multi-lead patch, Portable telemetry, Respiration, Sleep study monitor, Telemedicine bispectral index (BIS) Number of input channels 4 Resolution (Bits) 24 Interface type SPI Operating temperature range (°C) -20 to 85 Rating Catalog
DSBGA (YAF) 49 13.387056 mm² 3.694 x 3.624 VQFN (RGZ) 48 49 mm² 7 x 7
  • Integrated Signal Chain for ECG, Pace Detection, and Respiration Measurement
  • ECG Receiver
    • Four high resolution channels at low power of 0.42mW/channel
    • Flexible four leads selectable from six electrodes
    • Programmable gain: 1.25 to 9
    • Input-referred noise: 4µVPP in 150Hz BW
    • Differential input range: ±1V with Gain = 4
    • CMRR: -140dB
    • Data rate: 125SPS to 128kSPS
  • Pace Detection
    • On-chip digital pace detection algorithm on programmable two leads
    • High-speed 128kSPS pace output on two channels for software pace detection
  • Respiration
    • Low-noise of 24mΩPP with 2kΩ body impedance and 1kΩ defibrillator protection resistor on each electrode
    • Supports Sine and Square wave excitation
  • Other Features
    • Built-in right leg drive amplifier steerable to any electrode
    • DC lead-off detection, AC lead impedance detection, Wilson Center Terminal (WCT), Goldberger Central Terminals (GCT), test signals
    • Battery voltage monitoring
    • Flexible power-down and standby modes
    • Built-in oscillator, PLL, and reference
    • 1k sample main FIFO and 2k sample pace FIFO
    • SPI-compatible serial interface
    • Analog supply voltage 1: 3.15V to 5.25V
    • Analog supply voltage 2: 1.7V to 1.9V
    • I/O supply voltage: 1.65V to 3.6V
  • Supports systems meeting AAMI EC11, AMI EC13, AMI EC38, IEC60601-1, IEC60601-2-25, IEC60601-2-27, and IEC60601-2-51 standards
  • Integrated Signal Chain for ECG, Pace Detection, and Respiration Measurement
  • ECG Receiver
    • Four high resolution channels at low power of 0.42mW/channel
    • Flexible four leads selectable from six electrodes
    • Programmable gain: 1.25 to 9
    • Input-referred noise: 4µVPP in 150Hz BW
    • Differential input range: ±1V with Gain = 4
    • CMRR: -140dB
    • Data rate: 125SPS to 128kSPS
  • Pace Detection
    • On-chip digital pace detection algorithm on programmable two leads
    • High-speed 128kSPS pace output on two channels for software pace detection
  • Respiration
    • Low-noise of 24mΩPP with 2kΩ body impedance and 1kΩ defibrillator protection resistor on each electrode
    • Supports Sine and Square wave excitation
  • Other Features
    • Built-in right leg drive amplifier steerable to any electrode
    • DC lead-off detection, AC lead impedance detection, Wilson Center Terminal (WCT), Goldberger Central Terminals (GCT), test signals
    • Battery voltage monitoring
    • Flexible power-down and standby modes
    • Built-in oscillator, PLL, and reference
    • 1k sample main FIFO and 2k sample pace FIFO
    • SPI-compatible serial interface
    • Analog supply voltage 1: 3.15V to 5.25V
    • Analog supply voltage 2: 1.7V to 1.9V
    • I/O supply voltage: 1.65V to 3.6V
  • Supports systems meeting AAMI EC11, AMI EC13, AMI EC38, IEC60601-1, IEC60601-2-25, IEC60601-2-27, and IEC60601-2-51 standards

The AFE1594 is a family of multichannel, simultaneous sampling, 24-bit, delta-sigma (ΔΣ) analog-to-digital converters (ADCs) with built-in programmable gain Instrumentation Amplifiers (INAs), internal reference, and an on-chip PLL. The AFE supports digital pace pulse detection, thoracic impedance measurement and incorporates all of the features that are commonly required in medical electrocardiogram (ECG) and electroencephalogram (EEG) applications. Multiple AFE159x devices can be cascaded in high channel count systems. With high levels of integration and exceptional performance, the AFE159x enables the development of scalable medical instrumentation systems at significantly reduced size, power, and overall cost.

The AFE1594 is a family of multichannel, simultaneous sampling, 24-bit, delta-sigma (ΔΣ) analog-to-digital converters (ADCs) with built-in programmable gain Instrumentation Amplifiers (INAs), internal reference, and an on-chip PLL. The AFE supports digital pace pulse detection, thoracic impedance measurement and incorporates all of the features that are commonly required in medical electrocardiogram (ECG) and electroencephalogram (EEG) applications. Multiple AFE159x devices can be cascaded in high channel count systems. With high levels of integration and exceptional performance, the AFE159x enables the development of scalable medical instrumentation systems at significantly reduced size, power, and overall cost.
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AFE1594 ACTIVE Low-power 4-channel ECG AFE with lead-off & lead quality detection and FIFO Same device minus respiration and pace detection.
AFE159P4 ACTIVE Low-power 4-channel ECG AFE with pacemaker, lead-off & lead quality detection, and FIFO Same device minus respiration.

Technical documentation

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* Data sheet AFE159x Low-Power, 4-Channel, 24-Bit Analog Front-Ends for Bio-Potential Measurements datasheet (Rev. A) PDF | HTML 12 Nov 2024

Design & development

For additional terms or required resources, click any title below to view the detail page where available.

Evaluation board

AFE1594EVM — AFE1594 evaluation module

The AFE1594 evaluation kit is a development platform to evaluate the performance of AFE1594 for patient monitoring and diagnostic applications. AFE1594 is a family of multichannel, simultaneous-sampling 24-bit delta-sigma (ΔΣ) analog-to-digital converters (ADCs) with built-in programmable gain (...)
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Driver or library

AFE159RP4-DESIGN — AFE159RP4 design resources

The full data sheet and other design resources for this device are available here.
Supported products & hardware

Supported products & hardware

Products
Biosensing AFEs
  • AFE1594 — Low-power 4-channel ECG AFE with lead-off & lead quality detection and FIFO
  • AFE159P4 — Low-power 4-channel ECG AFE with pacemaker, lead-off & lead quality detection, and FIFO
  • AFE159RP3 — Low-power 3-channel ECG AFE with respiration, pacemaker, lead-off & lead quality detection, and FIFO
  • AFE159RP4 — Low-power 4-channel ECG AFE with respiration, pacemaker, lead-off & lead quality detection, and FIFO
Hardware development
Evaluation board
Request
Support software

TIDA-010280-DESIGN — TIDA-010280 user guide, design files, and firmware

With these downloadable design files, the TIDA-010280 reference design allows users to connect with the TI Simplelink Conncet mobile app for a real-time ECG, Respiration, Pace pulse and temperature demo.
Supported products & hardware

Supported products & hardware

Products
Biosensing AFEs
  • AFE1594 — Low-power 4-channel ECG AFE with lead-off & lead quality detection and FIFO
  • AFE159P4 — Low-power 4-channel ECG AFE with pacemaker, lead-off & lead quality detection, and FIFO
  • AFE159RP4 — Low-power 4-channel ECG AFE with respiration, pacemaker, lead-off & lead quality detection, and FIFO
Request
Support software

TIDA-010288-DESIGN — TIDA-010288 user guide, design files, and firmware

With these downloadable design files, the TIDA-010288 reference design allows users to connect with the TI Simplelink Conncet mobile app for a real-time AI-enabled ECG, Respiration, Pace pulse and temperature demo.
Supported products & hardware

Supported products & hardware

Products
Biosensing AFEs
  • AFE1594 — Low-power 4-channel ECG AFE with lead-off & lead quality detection and FIFO
  • AFE159P4 — Low-power 4-channel ECG AFE with pacemaker, lead-off & lead quality detection, and FIFO
  • AFE159RP4 — Low-power 4-channel ECG AFE with respiration, pacemaker, lead-off & lead quality detection, and FIFO
Request
Simulation tool

PSPICE-FOR-TI — PSpice® for TI design and simulation tool

PSpice® for TI is a design and simulation environment that helps evaluate functionality of analog circuits. This full-featured, design and simulation suite uses an analog analysis engine from Cadence®. Available at no cost, PSpice for TI includes one of the largest model libraries in the (...)
Request
Reference designs

TIDA-010280 — Small, wireless 6-lead ECG Holter monitor reference design with respiration, pace, and temperature

The wearable biosensing Holter monitor reference design provides an evaluation platform for TI’s latest offerings in continuous monitoring of vital signs such as electrocardiogram (ECG), heart rate, respiration, pace pulse, temperature, and motion. The design utilizes the AFE159RP4 for low-power, (...)
Design guide: PDF
Reference designs

TIDA-010288 — Edge-AI enabled wireless ECG Holter monitor reference design for real-time arrhythmia classification

The Edge-artificial intelligence (AI) ready wearable biosensing Holter reference design provides an evaluation platform for our latest offerings in continuous monitoring of vital signs such as electrocardiography (ECG), heart rate, respiration, pace pulse, temperature and motion. The design uses (...)
Design guide: PDF
Package Pins CAD symbols, footprints & 3D models
DSBGA (YAF) 49 Ultra Librarian
VQFN (RGZ) 48 Ultra Librarian
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