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ISO6421

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Noise-immune, dual-channel, 1 forward/1 reverse, digital isolator

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Data sheet

ISO6421

ACTIVE
Data sheet Order now

Product details

Number of channels 2 Rating Catalog Forward/reverse channels 1 forward / 1 reverse Integrated isolated power No Isolation rating Basic, Reinforced Default output High, Low Data rate (max) (Mbps) 150 Protocols GPIO, PWM, UART Surge isolation voltage (VIOSM) (VPK) 4000, 10400 Transient isolation voltage (VIOTM) (VPK) 4500, 7071 Withstand isolation voltage (VISO) (Vrms) 2500, 5000 CMTI (min) (V/µs) 200000 Operating temperature range (°C) -40 to 125 Supply voltage (max) (V) 5.5 Supply voltage (min) (V) 2.25 Propagation delay time (typ) (µs) 0.0062 Current consumption per channel (DC) (typ) (mA) 1.45 Current consumption per channel (1 Mbps) (typ) (mA) 2.325 Creepage (min) (mm) 4, 8 Clearance (min) (mm) 4, 8 TI functional safety category Functional Safety-Capable
Number of channels 2 Rating Catalog Forward/reverse channels 1 forward / 1 reverse Integrated isolated power No Isolation rating Basic, Reinforced Default output High, Low Data rate (max) (Mbps) 150 Protocols GPIO, PWM, UART Surge isolation voltage (VIOSM) (VPK) 4000, 10400 Transient isolation voltage (VIOTM) (VPK) 4500, 7071 Withstand isolation voltage (VISO) (Vrms) 2500, 5000 CMTI (min) (V/µs) 200000 Operating temperature range (°C) -40 to 125 Supply voltage (max) (V) 5.5 Supply voltage (min) (V) 2.25 Propagation delay time (typ) (µs) 0.0062 Current consumption per channel (DC) (typ) (mA) 1.45 Current consumption per channel (1 Mbps) (typ) (mA) 2.325 Creepage (min) (mm) 4, 8 Clearance (min) (mm) 4, 8 TI functional safety category Functional Safety-Capable
SOIC (D) 8 29.4 mm² 4.9 x 6 SOIC (DWV) 8 67.275 mm² 5.85 x 11.5
  • Functional Safety-Capable (Planned)
    • Documentation available to aid IEC 61508 system design
  • Up to 150Mbps data rate
  • Robust SiO2 isolation barrier:
    • Up to 5000VRMS isolation rating
    • Up to 10.4kV surge capability
    • Up to ±250kV/µs typical CMTI
    • Wide temperature range: –40°C to 125°C ambient operating
  • Supply range: 2.25V to 5.5V
  • Overvoltage Tolerant Inputs
  • Default output high (ISO642x) and low (ISO642xF) options
  • Low propagation delay: 10ns maximum at 5V, 12ns maximum at 3.3V
  • Supports SPI up to: 25MHz at 5V, 20.8MHz at 3.3V
  • Low pulse width distortion: 1.8ns maximum at 5V, 2.2ns maximum at 3.3V
  • Robust electromagnetic compatibility (EMC)
    • System-level ESD, EFT, and surge immunity
    • Low emissions
  • SOIC (D-8) Package
  • Wide-SOIC (DWV-8) Package
  • Safety-Related Certifications (Planned):
    • DIN EN IEC 60747-17 (VDE 0884-17)
    • UL 1577 and CSA CAS Notice No. 5A
    • IEC 62368-1, IEC 61010-1 and GB 4943.1 certifications
  • Functional Safety-Capable (Planned)
    • Documentation available to aid IEC 61508 system design
  • Up to 150Mbps data rate
  • Robust SiO2 isolation barrier:
    • Up to 5000VRMS isolation rating
    • Up to 10.4kV surge capability
    • Up to ±250kV/µs typical CMTI
    • Wide temperature range: –40°C to 125°C ambient operating
  • Supply range: 2.25V to 5.5V
  • Overvoltage Tolerant Inputs
  • Default output high (ISO642x) and low (ISO642xF) options
  • Low propagation delay: 10ns maximum at 5V, 12ns maximum at 3.3V
  • Supports SPI up to: 25MHz at 5V, 20.8MHz at 3.3V
  • Low pulse width distortion: 1.8ns maximum at 5V, 2.2ns maximum at 3.3V
  • Robust electromagnetic compatibility (EMC)
    • System-level ESD, EFT, and surge immunity
    • Low emissions
  • SOIC (D-8) Package
  • Wide-SOIC (DWV-8) Package
  • Safety-Related Certifications (Planned):
    • DIN EN IEC 60747-17 (VDE 0884-17)
    • UL 1577 and CSA CAS Notice No. 5A
    • IEC 62368-1, IEC 61010-1 and GB 4943.1 certifications
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Technical documentation

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Top documentation Type Title Format options Date
* Data sheet ISO642x General-Purpose, Basic and Reinforced , Dual -Channel Digital Isolators datasheet (Rev. A) PDF | HTML 24 Mar 2026
Functional safety information ISO6421 and ISO6421-Q1 Functional Safety FIT Rate, FMD and Pin FMA PDF | HTML 03 Feb 2026
Product overview Eliminating Back-Powering in Digital Isolators With Over- Voltage Tolerant Inputs PDF | HTML 27 Jan 2026
Product overview Protecting Your Digital Isolator Using Overvoltage Tolerant Inputs PDF | HTML 27 Jan 2026
Technical article Why signal isolation matters in 48-V HEV/EV systems (Rev. A) PDF | HTML 10 Nov 2025
Application brief How to Isolate Signal and Power in Isolated CAN Systems (Rev. D) PDF | HTML 07 Nov 2025
Product overview Isolating UART Signals (Rev. B) PDF | HTML 07 Nov 2025

Design & development

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Evaluation board

DIGI-ISO-EVM — Universal digital isolator evaluation module

DIGI-ISO-EVM is an evaluation module (EVM) used to evaluate any of the TI single-channel, dual-channel, triple-channel, quad-channel or six-channel digital isolator devices in five different packages - 8-pin narrow-body SOIC (D), 8-pin wide-body SOIC (DWV), 16-pin wide-body SOIC (DW), 16-pin ultra- (...)

User guide: PDF | HTML
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Evaluation board

ISO64XX-WB-EVM — ISO64xx wide-body package evaluation module

The ISO64xx wide-body (WB) package evaluation module (EVM) allows designers to evaluate device performance for fast development and analysis of isolated systems. The EVM supports evaluation of any of the ISO64xx single-channel, dual-channel, quad-channel or six-channel digital isolator devices in (...)
User guide: PDF | HTML
Not available on TI.com
Simulation model

ISO6421 IBIS Model

SLLM517.ZIP (46 KB) - IBIS Model
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Package Pins CAD symbols, footprints & 3D models
SOIC (D) 8 Ultra Librarian
SOIC (DWV) 8 Ultra Librarian
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